Drug class: Iron products. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Case G. Maintaining iron balance with total-dose infusion of intravenous iron dextran. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. A healthcare provider will give you this injection. Minor/Significance Unknown.iron sucrose increases levels of calcium carbonate by enhancing GI absorption. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Venofer treatment may be repeated if iron deficiency reoccurs. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. 2015: 763576. INDICATIONS AND USAGE: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. J Lab Clin Med. STORAGE: Consult the product instructions and your pharmacist for storage details. The prevention and treatment of iron deficiency is a major public health goal, especially in women, children, and individuals in low-income countries. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. The dosage of Venofer is expressed in mg of elemental iron. This site contains information for licensed healthcare professionals in the United States. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. Contraindicated. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet Administration: I. Applies only to oral form of both agents. Only administer Venofer when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. (See also Notes section. This may be helped by giving the medication more slowly or at a lower dose. Applies only to oral form of both agents. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Minor/Significance Unknown. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. Give each dose as 15 mg/kg body weight for a total cumulative dose not to exceed 1500 mg of iron per course. J Med. Applies only to oral form of both agents. Each mL contains 20 mg of elemental . Due Date form Ultrasound Report. Use (s): Iron deficiency anemia in patients with chronic kidney disease (CKD) Applies only to oral form of both agents. Properly discard this product when it is expired or no longer needed. Found in multiple references. https://www.uptodate.com/ (Requires subscription). Administer Venofer only intravenously by slow injection or by infusion. Med J Aust; 193(9):525-32. commonly, these are "non-preferred" brand drugs or specialty DOSAGE AND ADMINISTRATION: Venofer must only be administered intravenously either by slow injection or by infusion. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Use Caution/Monitor. Each costs about $0.46 to $0.55 per mg of iron. Maximum single dose of iron sucrose to be given at a time in Non-dialysis CKD patients is 500 mg but with limited experience. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. You are encouraged to report Adverse Drug Events to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Serious - Use Alternative (1)iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Applies only to oral form of both agents. Applies only to oral form of both agents. Pediatric Patients: The most common adverse reactions (2%) are headache, respiratory tract viral infection, peritonitis, vomiting, pyrexia, dizziness, cough, nausea, arteriovenous fistula thrombosis, hypotension and hypertension. The original formula employs the weight in kg but users can input it in lbs and it gets transformed. pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Fulminant symptoms include confusion, sensation of passing out, paleness. Applies only to oral form of both agents. iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Mean change in Hgb from baseline to Week 5 2,5 After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. 1000 mg. 20 MINUTES. 5. A target haemoglobin value is also input so iron deficit can be determined according to a specified individual target. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. Since this is less than the threshold of total dose of 20 mg/kg, the deficit can be eliminated with a single infusion. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. LBW = Lean body weight in kg. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. Methods. Slowing the infusion rate may alleviate symptoms. iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. official version of the modified score here. Applies only to oral form of both agents. calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. This drug is available at the lowest co-pay. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Intravenous iron sucrose: establishing a safe dose. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Calculation of total iron deficit for initial repletion: [29] Total cumulative dose (mg) = [Target Hb Actual Hb] weight (kg) 2.4 + [15 weight (kg)] *Hb in g/dl: 2. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Avoid or Use Alternate Drug. 2010;18(3). Venofer [package insert]. Administer Injectafer intravenously, either as an undiluted slow intravenous push or by infusion. Reactions have occurred following the first dose or subsequent doses of Venofer. Use Caution/Monitor. Applies only to oral form of both agents. Applies only to oral form of both agents. There is no resource limitation, as if the tool was hosted on your site, so all your users can make use of it 24/7; The necessary tool updates will take place in real time with no effort on your end; A single click install to embed it into your pages, whenever you need to use it. Separate by at least 4 hours. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. Last updated on Jun 1, 2022. Venofer has not been studied in patients younger than 2 years old. Injection site discoloration has been reported following extravasation. For adult CKD patients on ESA therapy who are not receiving iron supplementation, the guideline suggests a trial of IV iron (or in NDD-CKD patients, alternatively, a 1- to 3-month trial of oral iron therapy) if: CKD=chronic kidney disease ESA=erythropoietin-stimulating agent Hb=hemoglobin IV=intravenous RBC=red blood cell WBC=white blood cell. Assure stable intravenous access to avoid extravasation. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. We'll do this entirely for free, as long as the calculator has applications for women's health. 1. Am J Kid Dis 2001; 38 988991. Do not administer Venofer to patients with iron overload. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Dosing: (a) Divide calculated total cumulate dose . The iron formulation choice remains for the clinician to make. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. The dosage of Venofer is expressed in mg of elemental iron. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Total dose iron infusion: safety and efficacy in predialysis patients. We comply with the HONcode standard for trustworthy health information. There are three fields in the parenteral iron replacement for iron deficiency anemia calculator: Weight can be input in either lbs or kilograms and the required transformations are performed by the calculator. Accessed: 4/12/2011. Hollands J, Foote E, Rodriguez A. Monitor Closely (1)famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Serious - Use Alternative (1)iron sucrose decreases levels of minocycline by inhibition of GI absorption. UpToDate. Discard unused portion. Applies only to oral form of both agents. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Other indications for IV are pregnancy iron deficiency, chronic renal impairment or need for rapid repletion. You can further save the PDF or print it. Anemia. In a randomized, open-label, dose-ranging trial for iron maintenance treatment with Venofer in pediatric patients with CKD on stable erythropoietin therapy [see Clinical Studies ( 14.7)], at least one adverse reaction was experienced by 57% (27/47) of the patients receiving Venofer 0.5 mg/kg, 53% (25/47) of the patients receiving Venofer 1 mg . 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Iron stores are input as default 500 mg on the assumption that the patient weight is greater or equal to 35 kg (77 lbs). . Use alternatives if available. Slow or stop the infusion if adverse reactions occur. Max Dose. Use Caution/Monitor. The total amount of INFeD in mL required to treat the anemia and replenish iron stores may be approximated as follows: Adults and Children over 15 kg (33 lbs): See Dosage Table. David McAuley, Pharm.D. Schweiz Med Wochenschr; 100(7):301-3. elemental iron (mg/ml) in the product being used: Where C= There are four fields that need to be completed: Weight body weight is used to establish iron deficit and is also taken into account when estimating the iron stores. Deferasirox chelates iron. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. Iron sucrose: 20 mg/mL. Most By entering this website, you acknowledge that you are a licensed healthcare professional practicing in the United States. Applies only to oral form of both agents. prescription products. Applies only to oral form of both agents. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. All Rights Reserved. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Either increases effects of the other by pharmacodynamic synergism. A: Generally acceptable. Avoid or Use Alternate Drug. Most Use Caution/Monitor.Minor (2)calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. Talk to your pharmacist for more details.During pregnancy, this medication should be used only when clearly needed. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Deferoxamine chelates iron. Anemia caused by the depletion of iron is called iron deficiency anemia. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . restrictions. Kumpf VJ. 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. FOR PATIENTS WEIGHING 50 kg OR MORE: Administer 1000 mg of Monoferric by intravenous infusion 20 minutes as a single dose 1. Avoid or Use Alternate Drug. FERAHEME met the predefined criteria for non-inferiority to Venofer . March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. If either is present, do not use the liquid. 2. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days. Indications: Ferrlecit is an iron replacement product for treatment of iron deficiency anemia in adult patients and in pediatric patients age 6 years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy. Interaction only with oral iron administration. Avoid or Use Alternate Drug. Applies only to oral form of both agents. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. Applies only to oral form of both agents. Monitor for signs and symptoms of hypotension following each Feraheme infusion. Accessed: 4/12/2011. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. If dose exceeds 20mg/kg it should be rounded down to 20mg/kg OR administration of the total dose has to be split and given 7 days apart. Applies only to oral form of both agents. ONE DOSE. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Applies only to oral form of both agents. Patients diagnosed with iron deficiency are prescribed iron supplementation, either to replete body stores or to correct anemia. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. It is important to note that the above calculations merely provide estimates and that individual dosage should be established by a medical professional based on the current package insert for the elemental iron product used. 1. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. The elemental iron product used is Iron sucrose 20 mg/mL. Injection: 50 mg/2.5 mL, 100 mg/5 mL, or 200 mg/10 mL (20 mg/mL) in single-dose vials. By taking into account the case of a patient weighing 78 kg (172 lbs) and having a hemoglobin level of 11 g/dL (110 g/L or 6.83 mmol/L). Use Caution/Monitor. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. Where: Medicine concentration Amount of active substance per a given volume of your drug. This drug is available at a higher level co-pay. Applies only to oral form of both agents. didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Iron stores 500 mg for body weight greater than or equal to 35 kg (77 lbs) and 15 mg/kg for body weight less than 35 kg. commonly, these are generic drugs. Use Caution/Monitor. Applies only to oral form of both agents. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to 1995 Mar-Apr;11(2):163-8. Applies only to oral form of both agents. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. This site complies with the HONcode standard for trust- worthy health information: verify here. Safety of highdose iron sucrose infusion in hospitalized patients with chronic kidney disease. Reference www.medicines.org.uk Background Each mL contains 20 mg of elemental iron. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. It varies from increases in dietary intake of iron (usually for prophylaxis purposes) to oral, intramuscular or intravenous therapy. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin, Do not mix with other medications or add to parenteral nutrition solutions for IV infusion, Do not dilute to concentrations below 1 mg/mL, Add dose to 0.9% NaCl infusion bags (PVC or non-PVC); final concentrations range is 1-2 mg of elemental iron/mL, Visually inspect for particulate matter and discoloration prior to infusion, Stable for 7 days at controlled room temperature (25C). Many patients with kidney disease cannot get enough iron from food and require injections. Adding plans allows you to compare formulary status to other drugs in the same class. All adult and pediatric patients receiving Venofer require periodic monitoring of hematologic and iron parameters (hemoglobin, hematocrit, serum ferritin and transferrin saturation). Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Applies only to oral form of both agents. FOR PATIENTS WEIGHING LESS THAN 50 kg: Administer Monoferric as 20 mg/kg actual body weight by intravenous infusion 20 minutes . Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Am J HealthSyst Pharm 2006;63:731735. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Use Caution/Monitor. Monitor Closely (1)pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. ]Venofer treatment may be repeated if iron deficiency reoccurs. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Suggested regime: Prescribing instructions Prescribing a single/first dose: 2010; 193(9):525-32. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage Recommended dosage for patients weighing 50kg (110lb) or more: Give Injectaferin two doses separated by at least 7 days. The iron deficit estimation is based on the Ganzoni formula: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. Schweiz Med Wochenschr. This topic . Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. Minor/Significance Unknown. I. The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDDCKD has not - been established. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Compare formulary status to other drugs in the same class. Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Last updated 28/06/2018 Enter values here and press 'Calculate'. Applies only to oral form of both agents. Avoid or Use Alternate Drug. J Lab Clin Med; 111(5):566-70. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. Parenteral iron supplementation. Applies only to oral form of both agents. Monitor Closely (1)iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Kidney Int. cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Minor (1)iron sucrose, benazepril. ------------------------------------------------------------------------- Iron Dextran Complex [ Infed ] Elemental iron: 50 mg of elemental iron per mL [2 mL] [package insert] BOXED WARNING: WARNING: RISK FOR ANAPHYLACTIC-TYPE REACTIONS Anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. Fill in the calculator/tool with your values and/or your answer choices and press Calculate. Modify Therapy/Monitor Closely. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. (2010) Diagnosis and management of iron deficiency anaemia: a clinical update. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. Get in touch with MDApp by using the following contact details: 2017 - 2023 MDApp. Applies only to oral form of both agents. 1) Ganzoni AM. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 - Hb in g/dL) x 2.145 Volume of product required in mL = Iron deficit in mg / C in mg/mL Where C is the concentration of the iron product: 50 mg/mL for Iron dextran; 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Dosing Administration & Considerations . Crown Rump Length and Nuchal Translucency. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Use Caution/Monitor. Assessing new treatment options, Intravenous iron-dextran: therapeutic and experimental possibilities.
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