In my view the paper isn't worth the pixels used to display it on a screen. You must log in or register to reply here. But that's just me. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to replacement therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. I'm just saying the evidence presented in this article isn't very strong, and more study is needed to show Synthroid causes lung cancer. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . Keep checking back for the register link to appear. Hypothyroidism reduces respiratory drive and can cause obstructive sleep apnea or pleural effusion, while hyperthyroidism increases respiratory drive and can cause dyspnea on exertion. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. I have posted the link, so you can see if it has any merit. The aim of the study was to assess the occurrence and nature of immune-related endocrine adverse events (irAEs) among patients with non-small-cell lung cancer (NSCLC) treated with nivolumab. If people do not wish to find out all they can about their disease that is fine too. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM. Due to excessive bot signups along with nefarious actors we are limiting forum registration. This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. Iodine - and the lack of it - is implicated in breast cancer, after all. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Brit Med J 1978, 1:210212. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. This website is for information purposes only. New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. In 2011 I switched docs and was put on Armour as he told me Synthroid and the like are poison and they do not work. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Yes, lung cancer patients can have these symptoms, but so do patients who have other cancers. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. Baked or Fried avocado fries [Vegetarian]. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Link posted. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. The very concept of "marketing" is at odds with the real nature of these materials, which has to do with the protection and expansion of our nature and potential. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Thyroid disease is a major public health concern worldwide. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. I have always found this condition a riddle. Maybe because they "treat" only with T4 and not T3? Join the Patient & Caregiver Network. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? This is a news report of the research, so I can't learn the details of how the science was conducted. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. But what can be done for patients who are at low [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. undefined will no longer be visible to you including posts, replies, and photos. Note: Only a member of this blog may post a comment. and our There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. 1). Tokushima J Exp Med 1991, 38:2535. Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. Increased sensitivity to cold. I have no further scientific evidence. Millions of people who were not only wrongly diagnosed with cancers and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. [6] Venditti P, Di Stefano L, Di Meo S: Oxidative stress in cold induced hyperthyroid state. There are several books out there written about the topic. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). It is worth reading. Is that what releases free radicals? However, I do not believe it was out of the blue now. Oops I have just bought my first jar of marmalade in over ten years! Endocrinol. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. I am going to go for a walk with my dog :)). [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Posted on: Monday, August 12th 2013 at 7:15 am Written By: Sayer Ji, Founder A new study has. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. El almacenamiento o acceso tcnico es necesario para crear perfiles de usuario para enviar publicidad, o para rastrear al usuario en una web o en varias web con fines de marketing similares. For more, visitGreenMedInfo.comand Facebook.com/GreenMedInfo, or sign up forGreenMedInfos free e-Newsletter. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. millions treated for hypothyroidism at risk for lung cancer. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. It's usually based on the results of blood tests. 500+ pages of Natural Medicine Alternatives and Information. [14] K A Woeber. CRF encompasses physical, emotional, and/or cognitive tiredness; is related to cancer or cancer treatments; and interferes with multiple dimensions of health-related quality of life (1-3).CRF is poorly understood, underrecognized, and undertreated. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. Methods: The study group included 35 patients (15 women, 20 men, 65.8 7.1 years) with NSCLC in stage IIIB (n = 16, 45.7%) and IV (n = 19,54.3%) who were treated with nivolumab. Endocrinology 2008, 149:22412250. [13] Hollowell JG, Staehling NW, Flanders WD. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer worldwide, according to GLOBOCAN. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. florence nightingale concept 2 via de boleto A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. Even in the mildest form, hypothyroidism affects the heart. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. Monaldi Arch Chest Dis 2003, 59:140145. See more of Keri Topouzian, D.O. I have so much to say about this I could write a book. Once I got on the medication, the symptoms disappeared. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. Thanks, I am not suggesting I believe in all that I see. Untreated hypothyroidism increases morbidity and mortality. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. If I can help someone, fine. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Perhaps she and I could co-author? Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. Nah, I would give this much credence. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. I had doctor after doctor tell me it was in my head or I was menopausal. Also this study finds no link with breast cancer, when others have found a link. Article published in Wakeup-World.Com. [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Post Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. I will respond more later onBut I will briefly say I was on Synthyroid from 1993 to 2011. Endocrinology 1985, 117:12011208. Oops, I just saw that I posted the same article. J Exp Biol 2010, 213:28992911. Angiology 2000, 51:S65S68. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. It does not necessarily imply one thing caused the other. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. J. Clin. Another recently approved drug is tepotinib (Tepmetko). The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. Just go on one of the thyroid sites and read the stories. I am convinced that my lung cancer is related to the thyroid/auto immune issues I've had for years. Thank you for posting it, I agree we all need as much knowledge as we can get! [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. Asesora y Consultora Web3 para empresas. I honestly do not know. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. I wish I could say that my story was atypical. Join the forum, it's quick and easy . 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. I very much appreciate the information you shared. I cried with joy when I found out there was something really wrong with me. I think part of sharing information here on Inspire is the discussions about the articles we share. They compared sale of, "However, the impression we get from our experience, Health, Studies, Supps & Pharmaceuticals. bear in the big blue house characters; colne times obituaries this week Menu Toggle. [13] Hollowell JG, Staehling NW, Flanders WD, et al. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism).
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